LivingGLP1
Sulfonylurea

Gliclazide

GLICLAZIDE

Agent
gliclazide
Dosing
titrated to target
Mechanism
Insulin secretagogue
Trials
1
Participants in these arms
32

Molecule level node. Arms of different doses of this comparator within a trial are combined into one arm.

Related

    Effects across outcomes

    Bayesian random effects estimate against the comparator of each analysis (usually placebo), posterior median and 95% credible interval. Green: clearly better; red: clearly worse.
    ConditionOutcomeWindowVersusEffect (95% CrI)SUCRA
    Type 2 diabetes (adults)HbA1c changeweeks 20 to 36 (target week 26)PlaceboMD -0.81 (-1.53 to 0.66)0.25
    Type 2 diabetes (adults)HbA1c changeweeks 20 to 36 (target week 26)PlaceboMD -0.39 (-1.29 to 0.91)0.24
    Type 2 diabetes (adults)Body weight change in kilograms (diabetes)weeks 20 to 36 (target week 26)PlaceboMD 3.21 (-4.05 to 12.50)0.18
    Type 2 diabetes (adults)Body weight change in kilograms (diabetes)weeks 20 to 36 (target week 26)PlaceboMD 2.60 (-4.65 to 10.87)0.20
    Type 2 diabetes (adults)Systolic blood pressure changeweeks 20 to 36 (target week 26)PlaceboMD 2.14 (-4.70 to 9.03)0.17
    Type 2 diabetes (adults)Systolic blood pressure changeweeks 20 to 36 (target week 26)PlaceboMD 2.59 (-4.66 to 9.91)0.18

    Trials