LivingGLP1
Short acting GLP-1 receptor agonist (injectable)

Beinaglutide injection

BEIN_SC

Mechanism
GLP-1 receptor agonist; exenatide twice daily and lixisenatide (half life about 2 to 4 hours); beinaglutide (recombinant human GLP-1; half life of minutes)
Trials
2
Participants in these arms
102

Effects across outcomes

Bayesian random effects estimate against the comparator of each analysis (usually placebo), posterior median and 95% credible interval. Green: clearly better; red: clearly worse.
ConditionOutcomeWindowVersusEffect (95% CrI)SUCRA
Type 2 diabetes (adults)HbA1c changeweeks 20 to 36 (target week 26)PlaceboMD -0.95 (-2.06 to 0.22)0.57
Type 2 diabetes (adults)Body weight change in kilograms (diabetes)weeks 20 to 36 (target week 26)PlaceboMD -2.78 (-8.92 to 3.27)0.75
Type 2 diabetes (adults)Level 2 or 3 hypoglycemia (participants)longest follow-upPlaceboHR 1.12 (0.25 to 4.56)0.62
Type 2 diabetes (adults)Serious adverse eventslongest follow-upPlaceboHR 0.51 (0.01 to 33.28)0.61

Trials