parallel randomized trial
S003076
Type 2 diabetes (adults)S003076
Design
Conduct and analysis
Arms
| Arm | Treatment | Background | Randomized | Analyzed | Completed treatment |
|---|---|---|---|---|---|
| A1 | Exenatide 10 ug subcutaneous twice daily Exenatide | metformin; lifestyle: not reported | 17 | 15 | |
| A2 | Insulin glargine Insulin glargine | metformin; lifestyle: not reported | 18 | 15 |
Baseline characteristics
As printed in the trial reports or registry, per arm or for the whole trial.
| Characteristic | Statistic | Exenatide 10 ug subcutaneous twice daily A1 | Insulin glargine A2 | Whole trial ALL |
|---|---|---|---|---|
| age | mean (years) | 52.73 | 53.00 | |
| age | sd (years) | 4.68 | 4.07 | |
| bmi | mean (kg/m2) | 37.47 | 34.00 | |
| bmi | sd (kg/m2) | 4.44 | 2.91 | |
| diabetes duration | mean (years) | 4.93 | 6.46 | |
| diabetes duration | sd (years) | 4.02 | 4.27 | |
| female | n | 30 | ||
| hba1c | mean (percent) | 8.43 | 8.10 | |
| hba1c | sd (percent) | 0.99 | 0.45 |
Analyses this trial contributes to
Results
6 adjudicated result lines, grouped by outcome. Open an outcome to see its values.
HbA1c change (4 lines; O01)
| Week | Arm | Statistic | Estimate | SE or SD | 95% CI | Events / N | Detail |
|---|---|---|---|---|---|---|---|
| 24 | A1 | final | 7.32 percent | 1.30 | 15 | not stated; completers; R0019855:Table 1 | |
| 24 | A1 | percent change | percent | 15 | not stated; completers; R0019855:Table 1 | ||
| 24 | A2 | final | 7.12 percent | 0.47 | 15 | not stated; completers; R0019855:Table 1 | |
| 24 | A2 | percent change | percent | 15 | not stated; completers; R0019855:Table 1 |
Discontinuation due to adverse events (1 lines; O26)
| Week | Arm | Statistic | Estimate | SE or SD | 95% CI | Events / N | Detail |
|---|---|---|---|---|---|---|---|
| A1 | events | 1 / 17 | not stated; randomized; R0019855:Figure 1 |
Discontinuation due to gastrointestinal adverse events (1 lines; O27E)
| Week | Arm | Statistic | Estimate | SE or SD | 95% CI | Events / N | Detail |
|---|---|---|---|---|---|---|---|
| A1 | events | 1 / 17 | not stated; randomized; nausea; R0019855:Figure 1 |