LivingGLP1
Oral small molecule GLP-1 receptor agonist

Vct220 po 160mg qd

VCT220_PO_160MG_QD

Mechanism
Nonpeptide GLP-1 receptor agonist (orforglipron; danuglipron; lotiglipron; aleniglipron and others)
Trials
0
Participants in these arms
0

Effects across outcomes

Bayesian random effects estimate against the comparator of each analysis (usually placebo), posterior median and 95% credible interval. Green: clearly better; red: clearly worse.
ConditionOutcomeWindowVersusEffect (95% CrI)SUCRA
Overweight or obesity without diabetes (adults)Serious adverse eventslongest follow-upPlaceboHR 0.29 (0.00 to 8.83)0.72
Overweight or obesity without diabetes (adults)Discontinuation due to adverse eventslongest follow-upPlaceboHR 0.89 (0.06 to 9.57)0.66
Overweight or obesity without diabetes (adults)Nausealongest follow-upPlaceboHR 7.39 (3.15 to 19.57)0.19
Overweight or obesity without diabetes (adults)Vomitinglongest follow-upPlaceboHR 5.25 (1.98 to 15.88)0.42
Overweight or obesity without diabetes (adults)Diarrhealongest follow-upPlaceboHR 2.76 (0.98 to 8.41)0.35

Trials