parallel randomized trial

S003070

Design

Randomized: 60
Start year
Treatment: 2 weeks, follow-up 2 weeks
Countries: China (1 sites)
Sponsor: (not reported)
Eligibility: newly diagnosed hospitalized T2D; age 25 to 70; HbA1c 9 to 14 percent; BMI 25 to 35

Arm	Treatment	Background	Randomized	Analyzed	Completed treatment
A1	Standard care or no added treatment CSII alone	CSII insulin aspart pump titrated to euglycemia; lifestyle: standard	30	30
A2	Liraglutide 1.8 mg subcutaneous once daily CSII plus liraglutide	CSII insulin aspart pump titrated to euglycemia; lifestyle: standard	30	30

As printed in the trial reports or registry, per arm or for the whole trial.

Characteristic	Statistic	Standard care or no added treatment A1	Liraglutide 1.8 mg subcutaneous once daily A2
age	median (years)	46.00	50.00
age	q1 (years)	42.50	42.50
age	q3 (years)	59.00	66.00
bmi	median (kg/m2)	29.74	27.30
bmi	q1 (kg/m2)	26.33	25.90
bmi	q3 (kg/m2)	29.98	28.72
female	n	3	7
hba1c	median (percent)	11.20	10.40
hba1c	q1 (percent)	9.30	10.30
hba1c	q3 (percent)	12.80	11.80
sbp	mean (mmHg)	139.00	136.27
sbp	sd (mmHg)	17.08	18.63
uacr: microalbuminuria	percent	16.67	13.33

9 adjudicated result lines, grouped by outcome. Open an outcome to see its values.

Body weight change in kilograms (diabetes) (2 lines; O02)

Week	Arm	Statistic	Estimate	SE or SD	95% CI	Events / N	Detail
2	A1	change	-0.47 kg	0.65		30	not stated; completers; R0024678:Table 3
2	A2	change	-1.25 kg	0.57		30	not stated; completers; R0024678:Table 3

Level 2 or 3 hypoglycemia (participants) (2 lines; O04)

Week	Arm	Statistic	Estimate	SE or SD	95% CI	Events / N	Detail
	A1	events				0 / 30	not stated; completers; R0024678:p5
	A2	events				0 / 30	not stated; completers; R0024678:p5

Nausea (1 lines; O27A)

Week	Arm	Statistic	Estimate	SE or SD	95% CI	Events / N	Detail
	A2	events	16.7			30	not stated; completers; R0024678:Table 3

Vomiting (1 lines; O27B)

Week	Arm	Statistic	Estimate	SE or SD	95% CI	Events / N	Detail
	A2	events	26.7			30	not stated; completers; R0024678:Table 3

Diarrhea (1 lines; O27C)

Week	Arm	Statistic	Estimate	SE or SD	95% CI	Events / N	Detail
	A2	events	10.0			30	not stated; completers; R0024678:Table 3

Discontinuation due to gastrointestinal adverse events (2 lines; O27E)

Week	Arm	Statistic	Estimate	SE or SD	95% CI	Events / N	Detail
	A1	events				0 / 30	not stated; completers; R0024678:p5
	A2	events				0 / 30	not stated; completers; R0024678:p5