LivingGLP1
Short acting GLP-1 receptor agonist (injectable)

Lixisenatide 30 µg injection twice daily

LIXI_SC_30UG_BID

Effects across outcomes

Bayesian random effects estimate against the comparator of each analysis (usually placebo), posterior median and 95% credible interval. Green: clearly better; red: clearly worse.
ConditionOutcomeWindowVersusEffect (95% CrI)SUCRA
Type 2 diabetes (adults)Level 2 or 3 hypoglycemia (participants)longest follow-upPlaceboHR 0.53 (0.01 to 29.54)0.46
Type 2 diabetes (adults)Level 2 or 3 hypoglycemia (participants)longest follow-upPlaceboHR 2.20 (0.70 to 7.07)0.34
Type 2 diabetes (adults)Serious adverse eventslongest follow-upPlaceboHR 0.48 (0.04 to 2.73)0.69
Type 2 diabetes (adults)Discontinuation due to adverse eventslongest follow-upPlaceboHR 2.22 (0.23 to 27.00)0.42
Type 2 diabetes (adults)Nausealongest follow-upPlaceboHR 5.38 (2.73 to 10.55)0.23
Type 2 diabetes (adults)Vomitinglongest follow-upPlaceboHR 4.99 (1.62 to 15.36)0.31
Type 2 diabetes (adults)Diarrhealongest follow-upPlaceboHR 3.01 (1.54 to 5.90)0.23
Type 2 diabetes (adults)Acute pancreatitislongest follow-upPlaceboHR 0.91 (0.05 to 16.65)0.46

Trials