LivingGLP1
Long acting GLP-1 receptor agonist (injectable)

Exenatide (ITCA 650 implant) 40 µg implant continuous

EXENIMP_IMPLANT_40UG_CONT

Mechanism
GLP-1 receptor agonist; daily or weekly (liraglutide; dulaglutide; semaglutide; exenatide extended release; albiglutide; efpeglenatide; loxenatide; taspoglutide and others)
Trials
1
Participants in these arms
51

Effects across outcomes

Bayesian random effects estimate against the comparator of each analysis (usually placebo), posterior median and 95% credible interval. Green: clearly better; red: clearly worse.
ConditionOutcomeWindowVersusEffect (95% CrI)SUCRA
Type 2 diabetes (adults)Serious adverse eventslongest follow-upPlaceboHR 0.38 (0.01 to 14.53)0.65
Type 2 diabetes (adults)Nausealongest follow-upPlaceboHR 5.03 (2.32 to 11.03)0.25
Type 2 diabetes (adults)Vomitinglongest follow-upPlaceboHR 5.97 (1.85 to 21.45)0.26
Type 2 diabetes (adults)Diarrhealongest follow-upPlaceboHR 3.45 (1.00 to 14.13)0.23
Type 2 diabetes (adults)Constipationlongest follow-upPlaceboHR 4.66 (0.80 to 32.08)0.20

Trials