LivingGLP1
Long acting GLP-1 receptor agonist (injectable)

Exenatide (ITCA 650 implant) 20 ug implant continuous

EXENIMP_IMPLANT_20UG_CONT

Agent
exenatide (ITCA 650 implant)
Route
IMPLANT
Dose
20 ug
Frequency
CONT
Dosing
fixed
Mechanism
GLP-1 receptor agonist; daily or weekly (liraglutide; dulaglutide; semaglutide; exenatide extended release; albiglutide; efpeglenatide; loxenatide; taspoglutide and others)
Trials
1
Participants in these arms
51

Dose per day.

Effects across outcomes

Bayesian random effects estimate against the comparator of each analysis (usually placebo), posterior median and 95% credible interval. Green: clearly better; red: clearly worse.
ConditionOutcomeWindowVersusEffect (95% CrI)SUCRA
Type 2 diabetes (adults)Serious adverse eventslongest follow-upPlaceboHR 4.12 (0.18 to 143)0.22
Type 2 diabetes (adults)Nausealongest follow-upPlaceboHR 3.21 (1.41 to 7.21)0.43
Type 2 diabetes (adults)Vomitinglongest follow-upPlaceboHR 3.80 (1.01 to 14.39)0.39
Type 2 diabetes (adults)Diarrhealongest follow-upPlaceboHR 0.75 (0.11 to 3.87)0.73
Type 2 diabetes (adults)Constipationlongest follow-upPlaceboHR 3.29 (0.53 to 24.92)0.29

Trials