parallel randomized trial
S003077
Other conditionsS003077
Design
Conduct and analysis
Arms
| Arm | Treatment | Background | Randomized | Analyzed | Completed treatment |
|---|---|---|---|---|---|
| A1 | liraglutide (NN2211) NN2211 1.25 ug/kg | lifestyle: none | 1 | ||
| A2 | liraglutide (NN2211) NN2211 5.0 ug/kg | lifestyle: none | 2 | ||
| A3 | liraglutide (NN2211) NN2211 7.5 ug/kg | lifestyle: none | 4 | ||
| A4 | liraglutide (NN2211) NN2211 10 ug/kg | lifestyle: none | 4 | ||
| A5 | liraglutide (NN2211) NN2211 12.5 ug/kg | lifestyle: none | 4 | ||
| A6 | Placebo Placebo | lifestyle: none | 10 |
Baseline characteristics
As printed in the trial reports or registry, per arm or for the whole trial.
| Characteristic | Statistic | NN2211 1.25 ug/kg A1 | NN2211 5.0 ug/kg A2 | NN2211 7.5 ug/kg A3 | NN2211 10 ug/kg A4 | NN2211 12.5 ug/kg A5 | Placebo A6 | Whole trial ALL |
|---|---|---|---|---|---|---|---|---|
| other male | n | 30 |
Results
37 adjudicated result lines, grouped by outcome. Open an outcome to see its values.
Serious adverse events (6 lines; O25)
| Week | Arm | Statistic | Estimate | SE or SD | 95% CI | Events / N | Detail |
|---|---|---|---|---|---|---|---|
| A1 | events | 0 / 1 | not stated; modified itt; R0027243:Results | ||||
| A2 | events | 0 / 2 | not stated; modified itt; R0027243:Results | ||||
| A3 | events | 0 / 4 | not stated; modified itt; R0027243:Results | ||||
| A4 | events | 0 / 4 | not stated; modified itt; R0027243:Results | ||||
| A5 | events | 0 / 4 | not stated; modified itt; R0027243:Results | ||||
| A6 | events | 0 / 10 | not stated; modified itt; R0027243:Results |
Discontinuation due to adverse events (6 lines; O26)
| Week | Arm | Statistic | Estimate | SE or SD | 95% CI | Events / N | Detail |
|---|---|---|---|---|---|---|---|
| A1 | events | 1 / 1 | not stated; modified itt; R0027243:Results | ||||
| A2 | events | 0 / 2 | not stated; modified itt; R0027243:Results | ||||
| A3 | events | 1 / 4 | not stated; modified itt; R0027243:Results | ||||
| A4 | events | 1 / 4 | not stated; modified itt; R0027243:Results | ||||
| A5 | events | 0 / 4 | not stated; modified itt; R0027243:Results | ||||
| A6 | events | 0 / 10 | not stated; modified itt; R0027243:Results |
Nausea (6 lines; O27A)
| Week | Arm | Statistic | Estimate | SE or SD | 95% CI | Events / N | Detail |
|---|---|---|---|---|---|---|---|
| A1 | events | 0 / 1 | not stated; modified itt; R0027243:Table 1 | ||||
| A2 | events | 0 / 2 | not stated; modified itt; R0027243:Table 1 | ||||
| A3 | events | 1 / 4 | not stated; modified itt; R0027243:Table 1 | ||||
| A4 | events | 3 / 4 | not stated; modified itt; R0027243:Table 1 | ||||
| A5 | events | 0 / 4 | not stated; modified itt; R0027243:Table 1 | ||||
| A6 | events | 1 / 10 | not stated; modified itt; R0027243:Table 1 |
Vomiting (6 lines; O27B)
| Week | Arm | Statistic | Estimate | SE or SD | 95% CI | Events / N | Detail |
|---|---|---|---|---|---|---|---|
| A1 | events | 0 / 1 | not stated; modified itt; R0027243:Table 1 | ||||
| A2 | events | 0 / 2 | not stated; modified itt; R0027243:Table 1 | ||||
| A3 | events | 1 / 4 | not stated; modified itt; R0027243:Table 1 | ||||
| A4 | events | 0 / 4 | not stated; modified itt; R0027243:Table 1 | ||||
| A5 | events | 0 / 4 | not stated; modified itt; R0027243:Table 1 | ||||
| A6 | events | 0 / 10 | not stated; modified itt; R0027243:Table 1 |
Diarrhea (6 lines; O27C)
| Week | Arm | Statistic | Estimate | SE or SD | 95% CI | Events / N | Detail |
|---|---|---|---|---|---|---|---|
| A1 | events | 0 / 1 | not stated; modified itt; R0027243:Table 1 | ||||
| A2 | events | 0 / 2 | not stated; modified itt; R0027243:Table 1 | ||||
| A3 | events | 0 / 4 | not stated; modified itt; R0027243:Table 1 | ||||
| A4 | events | 1 / 4 | not stated; modified itt; R0027243:Table 1 | ||||
| A5 | events | 1 / 4 | not stated; modified itt; R0027243:Table 1 | ||||
| A6 | events | 0 / 10 | not stated; modified itt; R0027243:Table 1 |
Constipation (6 lines; O27D)
| Week | Arm | Statistic | Estimate | SE or SD | 95% CI | Events / N | Detail |
|---|---|---|---|---|---|---|---|
| A1 | events | 0 / 1 | not stated; modified itt; R0027243:Table 1 | ||||
| A2 | events | 0 / 2 | not stated; modified itt; R0027243:Table 1 | ||||
| A3 | events | 0 / 4 | not stated; modified itt; R0027243:Table 1 | ||||
| A4 | events | 0 / 4 | not stated; modified itt; R0027243:Table 1 | ||||
| A5 | events | 0 / 4 | not stated; modified itt; R0027243:Table 1 | ||||
| A6 | events | 1 / 10 | not stated; modified itt; R0027243:Table 1 |
Discontinuation due to gastrointestinal adverse events (1 lines; O27E)
| Week | Arm | Statistic | Estimate | SE or SD | 95% CI | Events / N | Detail |
|---|---|---|---|---|---|---|---|
| A4 | events | 1 / 4 | not stated; modified itt; R0027243:Results |