crossover randomized trial

S002961

Name: LivingGLP1 adjudicated trial data and network meta-analysis results
Creator: Ahmad Sofi-Mahmudi
License: https://creativecommons.org/licenses/by/4.0/

Other conditionsS002961

Design

Randomized: 37
Start year
Treatment
Countries: China (1 sites)
Sponsor: Hangzhou Zhongmei Huadong Pharmaceutical (industry)
Eligibility: healthy Chinese adults 18 to 45, weight 50 kg or more, BMI 19 to 26

Conduct and analysis

Blinding: open label
Sequence generation: not reported
Allocation concealment: not reported
Outcome adjudication: not reported
Primary estimand: not stated
Analysis population
Missing data

Arms

Arm	Treatment	Background	Randomized	Analyzed	Completed treatment
A1	liraglutide Test liraglutide 0.6 mg single dose	lifestyle: not reported	37	36
A2	liraglutide Victoza 0.6 mg single dose	lifestyle: not reported	37	36

Baseline characteristics

As printed in the trial reports or registry, per arm or for the whole trial.

Characteristic	Statistic	Whole trial ALL
age	max (years)	41
age	mean (years)	27.3
age	min (years)	18
age	sd (years)	6.47
bmi	mean (kg/m2)	22.53
bmi	sd (kg/m2)	1.677
female	n	14
female	percent	38.9
other ethnicity han	n	34
other ethnicity han	percent	94.4
other ethnicity other nationalities	n	2
other ethnicity other nationalities	percent	5.6
weight	mean (kg)	62.04
weight	sd (kg)	6.890

Results

6 adjudicated result lines, grouped by outcome. Open an outcome to see its values.

Serious adverse events (2 lines; O25)

Week	Arm	Statistic	Estimate	SE or SD	95% CI	Events / N	Detail
	A1	events				0 / 36	not stated; safety; R0009787:Table 2
	A2	events				0 / 36	not stated; safety; R0009787:Table 2

Discontinuation due to adverse events (2 lines; O26)

Week	Arm	Statistic	Estimate	SE or SD	95% CI	Events / N	Detail
	A1	events				0 / 36	not stated; safety; R0009787:Table 2
	A2	events				0 / 36	not stated; safety; R0009787:Table 2

Discontinuation due to gastrointestinal adverse events (2 lines; O27E)

Week	Arm	Statistic	Estimate	SE or SD	95% CI	Events / N	Detail
	A1	events				0 / 36	not stated; safety; R0009787:Table 2
	A2	events				0 / 36	not stated; safety; R0009787:Table 2