GIP and GLP-1 receptor co-agonist
Tirzepatide 4.5 mg injection once weekly
TIRZ_SC_4p5MG_QW
Related
- All doses pooled: Tirzepatide injection
- Tirzepatide 1 mg subcutaneous once weekly
- Tirzepatide 5 mg subcutaneous once weekly
- Tirzepatide 10 mg subcutaneous once weekly
- Tirzepatide 15 mg subcutaneous once weekly
- Tirzepatide maximum tolerated dose injection once weekly
- Tirzepatide subcutaneous once weekly, maximum tolerated dose: 10 or 15 mg
- Tirzepatide 0.25 mg injection
- Tirzepatide 0.5 mg injection once weekly
- Tirzepatide 0.5 mg injection
- Tirzepatide 1 mg injection
- Tirzepatide 2.5 mg injection
- Tirzepatide 5 mg injection
- Tirzepatide 8 mg injection
- Tirzepatide 1.5 mg injection once weekly
- Tirzepatide 12 mg injection once weekly
Effects across outcomes
Bayesian random effects estimate against the comparator of each analysis (usually placebo), posterior median and 95% credible interval. Green: clearly better; red: clearly worse.
| Condition | Outcome | Window | Versus | Effect (95% CrI) | SUCRA |
|---|---|---|---|---|---|
| Type 2 diabetes (adults) | Serious adverse events | longest follow-up | Placebo | HR 0.53 (0.01 to 21.80) | 0.60 |
| Type 2 diabetes (adults) | Nausea | longest follow-up | Placebo | HR 3.55 (0.50 to 14.47) | 0.39 |
| Type 2 diabetes (adults) | Vomiting | longest follow-up | Placebo | HR 0.21 (0.00 to 2.84) | 0.88 |
| Type 2 diabetes (adults) | Diarrhea | longest follow-up | Placebo | HR 1.51 (0.11 to 8.53) | 0.51 |
| Type 2 diabetes (adults) | Constipation | longest follow-up | Placebo | HR 0.51 (0.00 to 14.52) | 0.67 |
| Type 2 diabetes (adults) | Acute pancreatitis | longest follow-up | Placebo | HR 0.95 (0.05 to 17.25) | 0.45 |