LivingGLP1
Long acting GLP-1 receptor agonist (injectable)

Semaglutide 0.05 mg injection once daily

SEMA_SC_0p05MG_QD

Effects across outcomes

Bayesian random effects estimate against the comparator of each analysis (usually placebo), posterior median and 95% credible interval. Green: clearly better; red: clearly worse.
ConditionOutcomeWindowVersusEffect (95% CrI)SUCRA
Overweight or obesity without diabetes (adults)Systolic blood pressure changeweeks 40 to 104 (target week 68)PlaceboMD -2.99 (-7.70 to 1.46)0.37
Overweight or obesity without diabetes (adults)Percent body weight changeweeks 40 to 104 (target week 68)PlaceboMD -3.56 (-7.06 to 0.01)0.18
Overweight or obesity without diabetes (adults)SF-36 physical component summary changeweeks 20 to 130 (target week 52)PlaceboMD 0.49 (-3.32 to 4.55)0.33
Overweight or obesity without diabetes (adults)Serious adverse eventslongest follow-upPlaceboHR 2.22 (0.88 to 5.50)0.29
Overweight or obesity without diabetes (adults)Nausealongest follow-upPlaceboHR 2.18 (1.32 to 3.55)0.74
Overweight or obesity without diabetes (adults)Vomitinglongest follow-upPlaceboHR 2.08 (0.81 to 5.14)0.74
Overweight or obesity without diabetes (adults)Diarrhealongest follow-upPlaceboHR 1.25 (0.62 to 2.53)0.69
Overweight or obesity without diabetes (adults)Constipationlongest follow-upPlaceboHR 1.63 (0.68 to 3.85)0.59

Trials