GLP1_NEW

Liraglutide plus metformin 1.2 to 1000 mg injection once daily

Name: LivingGLP1 adjudicated trial data and network meta-analysis results
Creator: Ahmad Sofi-Mahmudi
License: https://creativecommons.org/licenses/by/4.0/

LIRAMETF_SC_1p2-1000MG_QD

Trials: 2
Participants in these arms: 15

All doses pooled: Liraglutide and metformin injection
Liraglutide and metformin 1.2 to 0.85 mg injection once daily
Liraglutide and metformin 1.2 to 1500 mg injection once daily

Effects across outcomes

Bayesian random effects estimate against the comparator of each analysis (usually placebo), posterior median and 95% credible interval. Green: clearly better; red: clearly worse.

Condition	Outcome	Window	Versus	Effect (95% CrI)	SUCRA
Polycystic ovary syndrome	Nausea	longest follow-up	Placebo	HR 1.71 (0.36 to 7.90)	0.42
Polycystic ovary syndrome	Diarrhea	longest follow-up	Placebo	HR 2.96 (0.44 to 22.09)	0.27

Trials

NCT02909933
Low Dose Liraglutide and Metformin vs. High Dose Liraglutide Alone in Treatment of Obesity
2015 · 30 randomized · 12 weeks
NCT01911468
Short-term Combined Treatment With Liraglutide and Metformin Leads to Significant Weight Loss in Obese Women With Polycystic Ovary Syndrome and Previous Poor Response to Metformin
2011 · 40 randomized · 12 weeks

Liraglutide plus metformin 1.2 to 1000 mg injection once daily

Related

Effects across outcomes

Trials