The Effect of Different Treatment Options on Markers of Vascular, Myocardial and Endothelial Function in Women With Polycystic Ovary Syndrome and the Association With Metabolic and Hormonal Abnormalities of the Syndrome

Registration

Registration

NCT06889454

Study type

OBSERVATIONAL

Status

RECRUITING

Enrollment

120

Start

2024-02-01

Primary completion

2025-02-01

Lead sponsor

Attikon Hospital

Conditions

PCOS; Hyperinsulinism; Hyperandrogenism; Metabolic Syndrome

Interventions

DRUG:GLP-1 receptor agonist; DRUG:Oral contraceptive; DRUG:Metformin; OTHER:Lifestyle modification

Results posted

FALSE

Individual participant data sharing

UNDECIDED

Registered primary outcomes

• Τhe change in Global Longitudinal Strain during Oral glucose Tolerance Test [120 minute of Oral glucose Tolerance Test]
• The change in Pulse Wave Velocity during Oral glucose Tolerance Test [120minute of Oral glucose Tolerance Test]
• The change in Perfused Boundary Region during Oral glucose Tolerance Test [120minute of Oral glucose Tolerance Test]
• The change in Global Longitudinal Strain [six months]
• The change in Pulse Wave Velocity [six months]
• The change in Perfused Boundary Region [six months]
• The change in Metalloproteinase 9 [six months]