Dietary Pistachio Intake and Nutrition-Related Outcomes in Individuals Using GLP-1 Receptor Agonists: A Randomized Controlled Trial

Registration

Registration

NCT07244445

Study type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

NONE

Status

RECRUITING

Enrollment

108

Start

2026-01-29

Primary completion

2027-12

Lead sponsor

Ian J. Neeland, MD

Conditions

Dietary Change; Obesity & Overweight; Food Acceptance

Interventions

DIETARY_SUPPLEMENT:Pistachios; PROCEDURE:Dual-energy X-ray absorptiometry (DEXA) scans

Results posted

FALSE

Individual participant data sharing

NO

Registered primary outcomes

• Change is Satiety as measured by the Hunger and Satiety Visual Analog Scales (VAS) [Baseline, End of study (12 weeks)]
• Change in fatigue as measured by the Fatigue Severity VAS-F Survey [Baseline, End of study (12 weeks)]
• Change in mood/well-being as measured by the Mental clarity, energy levels, and motivation VAS. [Baseline, End of study (12 weeks)]
• Change in dietary quality as measured by Healthy Eating Index (HEI) [Baseline, End of study (12 weeks)]
• Change in food enjoyment as measured by the Food Pleasure Scale (FPS) [Baseline, End of study (12 weeks)]
• Change in fasting glucose as measured by medical record review [Baseline, End of study (12 weeks)]
• Change in HbA1c as measured by medical record review [Baseline, End of study (12 weeks)]
• Change in total cholesterol as measured by medical record review [Baseline, End of study (12 weeks)]
• Change in LDL-C as measured by medical record review [Baseline, End of study (12 weeks)]
• Change in HDL-C as measured by medical record review [Baseline, End of study (12 weeks)]
• Change in triglycerides as measured by medical record review [Baseline, End of study (12 weeks)]
• Change in physical activity as measured by International Physical Activity Questionnaire (IPAQ) [Baseline, End of study (12 weeks)]