Study S002632

PROACT 3: Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health

Name: LivingGLP1 adjudicated trial data and network meta-analysis results
Creator: Ahmad Sofi-Mahmudi
License: https://creativecommons.org/licenses/by/4.0/

ClinicalTrials.gov record

Registration

Registration: NCT07087431
Acronym: PROACT 3
Study type: INTERVENTIONAL
Allocation: RANDOMIZED
Masking: DOUBLE
Status: RECRUITING
Enrollment: 500
Start: 2025-10-15
Primary completion: 2026-10-15
Lead sponsor: Massachusetts General Hospital
Conditions: Coronary Artery Disease
Interventions: BEHAVIORAL:Immediate disclosure of CAD PRS results; BEHAVIORAL:Deferred Disclosure of CAD PRS results
Results posted: FALSE
Individual participant data sharing: YES
Secondary identifiers: NIH:R01HL164629

Registered primary outcomes

Change in low-density lipoprotein cholesterol (LDL-C) from baseline to 12 months [12 months]

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