Study S002630

Effects of Incretins on Human Platelet Function

Name: LivingGLP1 adjudicated trial data and network meta-analysis results
Creator: Ahmad Sofi-Mahmudi
License: https://creativecommons.org/licenses/by/4.0/

ClinicalTrials.gov record

Registration

Registration: NCT01408862
Study type: OBSERVATIONAL
Status: COMPLETED
Enrollment: 20
Start: 2012-12
Primary completion: 2014-08
Lead sponsor: National Council of Scientific and Technical Research, Argentina
Conditions: Inhibition of Platelet Aggregation by Incretins
Interventions: OTHER:venous puncture
Results posted: TRUE

Registered primary outcomes

Expression of Glucagon Like Peptide -1 (GLP-1) and Gastric Inhibitory Peptide (GIP) Receptors in Normal Human Platelets [Platelets drawn from a volunteer were evaluated 1 time (in 1-2 days)]
Changes in Basal or Aggregant-induced Platelet Activation (With and Without Glucose Added to the Media, 200 mg/dl, 400 mg/dL) by GLP-1-(7-36)NH2 and Its Metabolite (GLP-1-(9-36)NH2)and a GIP Agonist at Different Concentrations. [Platelets drawn from a volunteer will be evaluated 1 time (in 1-2 days)]

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