Study S002534
Glycemic Velocity as a Modifiable Determinant of Early Retinal Microvascular and Choroidal Change During Initiation of GLP-1 Receptor Agonist Versus SGLT2 Inhibitor Therapy in Type 2 Diabetes: A Prospective Multimodal Retinal Imaging Cohort Study (the GLIDE Study)
Registration
Registered primary outcomes
- Change in parafoveal deep-capillary-plexus (DCP) vessel density on OCT angiography [Baseline to Month 3]
Linked records (5)
Automatic links, confirmed or rejected during screening. A record citing this registration may be a secondary analysis, a commentary or a review that mentions the trial.
| Record | Title | Year | Design | Identifiers | Link basis |
|---|---|---|---|---|---|
| R0001072 | GLP-1 receptor agonists in eye disease: a comprehensive review of current research and future potential. Luo Y, BMC ophthalmology | 2026 | Systematic review | PMID 41501669DOI | registry reference BACKGROUND:41501669 |
| R0006278 | Risk of diabetic retinopathy and diabetic macular oedema with sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 receptor agonists in type 2 diabetes: a real-world data study from a global federated database. Eleftheriadou A, Diabetologia | 2024 | Nonrandomized study | PMID 38584180DOI | registry reference BACKGROUND:38584180 |
| R0004204 | GLP-1 receptor agonists and diabetic retinopathy: A meta-analysis of randomized clinical trials. Kapoor I, Survey of ophthalmology | 2023 | Systematic review | PMID 37454782DOI | registry reference BACKGROUND:37454782 |
| R0028636 | Worsening of diabetic retinopathy with rapid improvement in systemic glucose control: A review. Bain SC, Diabetes, obesity & metabolism | 2019 | Narrative review | PMID 30226298DOI | registry reference BACKGROUND:30226298 |
| R0022278 | Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes. Marso SP, The New England journal of medicine | 2016 | Randomized trial | PMID 27633186DOI | registry reference BACKGROUND:27633186 |