Liraglutide Effects on Memory in Healthy Subjects

Registration

Registration

NCT01550653

Study type

INTERVENTIONAL

Allocation

RANDOMIZED

Phase

PHASE1

Masking

TRIPLE

Status

COMPLETED

Enrollment

40

Start

2012-05

Primary completion

2013-12

Lead sponsor

University of Luebeck

Conditions

Healthy

Interventions

DRUG:liraglutide; DRUG:Placebo

Results posted

FALSE

Registered primary outcomes

• Change from Baseline in the immediate and delayed recall of a declarative memory task (word list recall) at time points indicated in "time frame" section. [Day -7 (immediate Recall 1), Day 0 (Delayed Recall 1), Day 1 (Immediate Recall 2), Day 7 (Delayed Recall 2), Day 28 (Immediate Recall 3), Day 35 (Delayed Recall 3)]
• Change from baseline in the immediate and delayed recall of an Episodic Memory Task (story recall) at the time points indicated in the "Time Frame" - section. [Day -7 (immediate Recall 1), Day 0 (Delayed Recall 1), Day 28 (Immediate Recall 2), Day 35 (Delayed Recall 2)]
• Change from baseline in performance on a two-dimensional object location task on day 1 and day 35. [Day -7, Day 1, Day 35]
• Change from baseline in performance on a working-memory task on day 1 and day 35. [Day -7, Day 1, Day 35]
• Change from baseline in immediate and delayed recall of a procedural memory task at the time points indicated in the "Time Frame" - section. [Day -7 (immediate Recall 1), Day 0 (Delayed Recall 1), Day 28 (Immediate Recall 2), Day 35 (Delayed Recall 2)]