Study S002258

A Phase 3b, Randomized, Multicenter, Controlled Study of Mirikizumab and Placebo or Mirikizumab Concomitantly Administered With Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight

ClinicalTrials.gov record

Registration

Registration: NCT06937086
Acronym: COMMIT-UC
Study type: INTERVENTIONAL
Allocation: RANDOMIZED
Phase: PHASE3
Masking: DOUBLE
Status: RECRUITING
Enrollment: 350
Start: 2025-06-26
Primary completion: 2028-04
Lead sponsor: Eli Lilly and Company
Conditions: Ulcerative Colitis; Obesity or Overweight
Interventions: DRUG:Mirikizumab; DRUG:Tirzepatide; DRUG:Placebo
Results posted: FALSE
Individual participant data sharing: YES
Secondary identifiers: CTIS:2024-520209-38-00; OTHER:I6T-MC-AMCD

Registered primary outcomes

Percentage of Participants Who Simultaneously Achieve Clinical Remission and at Least 10% Weight Reduction [Week 52]

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