Study S002215

Novel Perioperative Optimization of Obese Osteoarthritic Patients Pending Total Knee Replacement With Glucagon-like Peptide-1 Receptor Agonist (NPO-OOPS-TKR)

Name: LivingGLP1 adjudicated trial data and network meta-analysis results
Creator: Ahmad Sofi-Mahmudi
License: https://creativecommons.org/licenses/by/4.0/

ClinicalTrials.gov record

Registration

Registration: NCT06807970
Acronym: NPO-OOPS-TKR
Study type: INTERVENTIONAL
Allocation: RANDOMIZED
Phase: EARLY_PHASE1
Masking: DOUBLE
Status: ACTIVE_NOT_RECRUITING
Enrollment: 54
Start: 2025-09-01
Primary completion: 2027-07-01
Lead sponsor: The University of Hong Kong
Conditions: Osteoarthritis (OA) of the Knee
Interventions: DRUG:Glucagon-like peptide-1 receptor agonists (GLP 1 RA); OTHER:Control (Standard treatment)
Results posted: FALSE
Individual participant data sharing: NO

Registered primary outcomes

Visual analogue scale and analgesic consumption [As part of the standard of care when undergoing TKR, patients are routinely assessed at enrolment, 1 month and same day before surgery, and at 6 weeks,3 months, 6 months and 12 months post-surgery.]

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