LivingGLP1
Study S002102

Effect and Safety of Semaglutide Once-weekly in East Asian Subjects With Overweight or Obesity

Registration

Registration
NCT03811574
Acronym
STEP 6
Study type
INTERVENTIONAL
Allocation
RANDOMIZED
Phase
PHASE3
Masking
QUADRUPLE
Status
COMPLETED
Enrollment
401
Start
2019-01-21
Primary completion
2020-11-20
Lead sponsor
Novo Nordisk A/S
Conditions
Overweight; Obesity
Interventions
DRUG:Semaglutide; DRUG:Placebo (semaglutide)
Results posted
TRUE
Individual participant data sharing
YES
Secondary identifiers
OTHER:U1111-1201-1629

Registered primary outcomes

  • Change in Body Weight (%) [Baseline (week 0), week 68]
  • Number of Participants Who Achieve (Yes/no): Body Weight Reduction More Than or Equal to 5% [At week 68]

Linked records (3)

Automatic links, confirmed or rejected during screening. A record citing this registration may be a secondary analysis, a commentary or a review that mentions the trial.
RecordTitleYearDesignIdentifiersLink basis
R0017452Effect of once-weekly subcutaneous semaglutide on abdominal visceral fat area in Japanese adults with overweight and obesity: A post hoc analysis of the STEP 6 trial.
Kadowaki T, Obesity research & clinical practice
2025Randomized trialPMID 40189961DOIcites ClinicalTrials.gov:NCT03811574; registry reference DERIVED:40189961
R0022193Semaglutide once a week in adults with overweight or obesity, with or without type 2 diabetes in an east Asian population (STEP 6): a randomised, double-blind, double-dummy, placebo-controlled, phase 3a trial.
Kadowaki T, The lancet. Diabetes & endocrinology
2022Randomized trialPMID 35131037DOIcites ClinicalTrials.gov:NCT03811574; registry reference DERIVED:35131037
R0020651Semaglutide 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial.
Davies M, Lancet (London, England)
2021Randomized trialPMID 33667417DOIregistry reference RESULT:33667417