Study S002055

Emulation of the REWIND Cardiovascular Outcomes Trial in Healthcare Claims Data.

Name: LivingGLP1 adjudicated trial data and network meta-analysis results
Creator: Ahmad Sofi-Mahmudi
License: https://creativecommons.org/licenses/by/4.0/

ClinicalTrials.gov record Study Protocol (PDF)

Registration

Registration: NCT07417631
Study type: OBSERVATIONAL
Status: COMPLETED
Enrollment: 300000
Start: 2026-02-03
Primary completion: 2026-06-15
Lead sponsor: Brigham and Women's Hospital
Conditions: Type 2 Diabetes
Interventions: DRUG:Dulaglutide; DRUG:Sitagliptin
Results posted: FALSE

Registered primary outcomes

Time to first occurrence of myocardial infarction, stroke, or all-cause mortality [From cohort entry through first occurrence of outcome, disenrollment, end of the study period, treatment discontinuation +45-day grace/risk window, treatment switch between arms, nursing home admission, start of another GLP-1 RA, assessed up to 1 year.]

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