LivingGLP1
Study S001770

31P-MRS and MRI Imaging in Semaglutide Study

Registration

Registration
NCT07695454
Study type
OBSERVATIONAL
Status
RECRUITING
Enrollment
10
Start
2026-07-30
Primary completion
2026-12-30
Lead sponsor
The Cleveland Clinic
Conditions
Type 2 Diabetes; BMI Greater Than 30
Interventions
RADIATION:31P-MRS and MRI
Results posted
FALSE
Individual participant data sharing
NO

Registered primary outcomes

  • Effects of semaglutide therapy on patients muscle mitochondrial function as quantified using phosphorous MR spectroscopy. [6 months]
  • Effects of semaglutide therapy on patients muscle fatty infiltration measured by MR relaxation time (T1, T2 and T1rho) mapping. [6 months]
  • Effects of semaglutide therapy on patients measured by hand grip. [6 months]
  • Effects of semaglutide therapy on patients measured by MRI. [6 months]
  • Effects of semaglutide therapy on patients muscle composition measured by MR relaxation time (T1, T2 and T1rho) mapping. [6 months]
  • Effects of semaglutide therapy on patients muscle composition measured by MR water-fat imaging. [6 months]
  • Effects of semaglutide therapy on patients muscle fatty infiltration measured by MR water-fat imaging. [6 months]
  • Effects of semaglutide therapy on patients muscle fatty infiltration measured by MR relaxation time (T1, T2 and T1rho) mapping [6 months]

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