Study S001753

A Comparison of the Haemodynamic and Metabolic Effects of Intravenous Glucagon-like Peptide-1, Glucagon and Glucagon-like Peptide-1:Glucagon Co-agonism in Healthy Male Participants

Included trial: extracted data ClinicalTrials.gov record

Registration

Registration: NCT03835013
Acronym: COCOA
Study type: INTERVENTIONAL
Allocation: RANDOMIZED
Masking: SINGLE
Status: COMPLETED
Enrollment: 26
Start: 2019-02-11
Primary completion: 2021-11-01
Lead sponsor: Cambridge University Hospitals NHS Foundation Trust
Conditions: Cardiovascular Diseases
Interventions: DRUG:Saline 0.9%; DRUG:Glucagon (25ng/kg/min); DRUG:Glucagon (50ng/kg/min); DRUG:Exenatide
Results posted: FALSE
Secondary identifiers: OTHER:18/EM/0417; OTHER:250402

Registered primary outcomes

Changes in haemodynamic parameters following intravenous infusion of 0.9% saline, glucagon, exenatide and their combination. [Comparison between 2 hour infusion visit 1-2 (Part A) / 1 hour infusion visit 1-4 (Part B), over a maximum period of 15 weeks]

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