Study S001734

Effect of Liraglutide on Body Weight and Pain in Overweight or Obese Patients With Knee Osteoarthritis: A Randomised, Double Blind, Placebo-controlled, Parallel Group, Single-centre Trial

Name: LivingGLP1 adjudicated trial data and network meta-analysis results
Creator: Ahmad Sofi-Mahmudi
License: https://creativecommons.org/licenses/by/4.0/

Included trial: extracted data ClinicalTrials.gov record

Registration

Registration: NCT02905864
Acronym: LOSEIT
Study type: INTERVENTIONAL
Allocation: RANDOMIZED
Phase: PHASE4
Masking: QUADRUPLE
Status: COMPLETED
Enrollment: 150
Start: 2016-11
Primary completion: 2019-02
Lead sponsor: Henrik Gudbergsen
Conditions: Osteoarthritis; Obesity
Interventions: DRUG:Liraglutide 3 mg (Saxenda); DRUG:Liraglutide 3 mg placebo
Results posted: FALSE
Individual participant data sharing: NO

Registered primary outcomes

Change in body weight [Week 0 to 52]
KOOS pain subscale [Week 0 to 52]

Linked records (5)

Automatic links, confirmed or rejected during screening. A record citing this registration may be a secondary analysis, a commentary or a review that mentions the trial.

Record	Title	Year	Design	Identifiers	Link basis
R0005808	Effect of weight loss and liraglutide on neutrophil gelatinase-associated lipocalin levels among individuals with overweight and knee osteoarthritis: Exploratory analyses of a randomized controlled trial. Poulsen AS, Osteoarthritis and cartilage open	2025	Randomized trial	PMID 39877802 DOI	cites ClinicalTrials.gov:NCT02905864; registry reference DERIVED:39877802
R0023750	Liraglutide after diet-induced weight loss for pain and weight control in knee osteoarthritis: a randomized controlled trial. Gudbergsen H, The American journal of clinical nutrition	2021	Randomized trial	PMID 33471039 DOI	cites ClinicalTrials.gov:NCT02905864; registry reference DERIVED:33471039
R0013522	Effect of liraglutide on body weight and pain in patients with overweight and knee osteoarthritis: protocol for a randomised, double-blind, placebo-controlled, parallel-group, single-centre trial. Gudbergsen H, BMJ open	2019	Protocol	PMID 31061017 DOI	cites ClinicalTrials.gov:NCT02905864; registry reference DERIVED:31061017
R0054183	Fluorescence Optical Imaging of Juvenile Arthritis S. G. Werner, The Journal of Rheumatology	2011	Randomized trial	PMID 21724713 DOI	cites ClinicalTrials.gov:NCT02905864
R0043174	Too many heart patients discharged without follow-up care Zosia Kmietowicz, BMJ	2005	Randomized trial	PMID 15947381 DOI	cites ClinicalTrials.gov:NCT02905864