LivingGLP1
Study S001491

The Physiological Effects of GLP-1 on Haemodynamics During Exercise in Patients With Ischaemic Heart Disease

Included trial: extracted dataClinicalTrials.gov record

Registration

Registration
NCT02315001
Acronym
LIONESS
Study type
INTERVENTIONAL
Allocation
RANDOMIZED
Phase
PHASE2
Masking
TRIPLE
Status
COMPLETED
Enrollment
26
Start
2014-01
Primary completion
2015-03
Lead sponsor
King's College London
Conditions
Ischaemic Heart Disease; Coronary Heart Disease; Chronic Stable Angina
Interventions
DRUG:Liraglutide; OTHER:Placebo
Results posted
FALSE
Secondary identifiers
OTHER_GRANT:FS/11/70/28917

Registered primary outcomes

  • Change in rate pressure product at 0.1 mV ST-segment depression [Following consecutive exercise treadmill tests performed at Week 2, Week3, Week 5 and Week 6 of a 6-week study protocol]
  • Change in degree of ST-segment depression at peak exercise [Following consecutive exercise treadmill tests performed at Week 2, Week3, Week 5 and Week 6 of a 6-week study protocol]

Linked records (2)

Automatic links, confirmed or rejected during screening. A record citing this registration may be a secondary analysis, a commentary or a review that mentions the trial.
RecordTitleYearDesignIdentifiersLink basis
R0018990Liraglutide to Improve corONary haemodynamics during Exercise streSS (LIONESS): a double-blind randomised placebo-controlled crossover trial.
Myat A, Diabetology & metabolic syndrome
2021Randomized trialPMID 33579317DOIcites ClinicalTrials.gov:NCT02315001; registry reference DERIVED:33579317
R0011211Design and rationale for the randomised, double-blinded, placebo-controlled Liraglutide to Improve corONary haemodynamics during Exercise streSS (LIONESS) crossover study.
Myat A, Cardiovascular diabetology
2015ProtocolPMID 25848859DOIcites ClinicalTrials.gov:NCT02315001; registry reference BACKGROUND:25848859