Study S001109

Does a GLP-1 Receptor Agonist Change Glucose Tolerance in Antipsychotic-treated Patients? A Randomized, Double-blinded, Placebo-controlled Clinical Trial

Name: LivingGLP1 adjudicated trial data and network meta-analysis results
Creator: Ahmad Sofi-Mahmudi
License: https://creativecommons.org/licenses/by/4.0/

ClinicalTrials.gov record

Registration

Registration: NCT01845259
Acronym: GREAT
Study type: INTERVENTIONAL
Allocation: RANDOMIZED
Phase: PHASE2
Masking: QUADRUPLE
Status: UNKNOWN
Enrollment: 103
Start: 2013-04
Primary completion: 2016-03
Lead sponsor: Psychiatric Centre Rigshospitalet
Conditions: Impaired Glucose Tolerance Associated With Drugs
Interventions: DRUG:Liraglutide; DRUG:Liraglutide Placebo
Results posted: FALSE
Secondary identifiers: EUDRACT_NUMBER:2013-000121-31; REGISTRY:U1111-1128-3404

Registered primary outcomes

Glucose tolerance [Baseline - 16 weeks]

Linked records (3)

Automatic links, confirmed or rejected during screening. A record citing this registration may be a secondary analysis, a commentary or a review that mentions the trial.

Record	Title	Year	Design	Identifiers	Link basis
R0016720	Effect of Liraglutide Treatment on Prediabetes and Overweight or Obesity in Clozapine- or Olanzapine-Treated Patients With Schizophrenia Spectrum Disorder: A Randomized Clinical Trial. Larsen JR, JAMA psychiatry	2017	Randomized trial	PMID 28601891 DOI	cites ClinicalTrials.gov:NCT01845259; registry reference DERIVED:28601891
R0019965	GLP-1 receptor agonist liraglutide reverses long-term atypical antipsychotic treatment associated behavioral depression and metabolic abnormalities in rats. Sharma AN, Metabolic brain disease	2015	Preclinical	PMID 25023888 DOI	cites ClinicalTrials.gov:NCT01845259; registry reference DERIVED:25023888
R0022025	Does a GLP-1 receptor agonist change glucose tolerance in patients treated with antipsychotic medications? Design of a randomised, double-blinded, placebo-controlled clinical trial. Larsen JR, BMJ open	2014	Randomized trial	PMID 24667381 DOI	cites ClinicalTrials.gov:NCT01845259; cites EudraCT:2013-000121-31; registry reference DERIVED:24667381