Study S001084

A Randomized Clinical Trial of Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion

Name: LivingGLP1 adjudicated trial data and network meta-analysis results
Creator: Ahmad Sofi-Mahmudi
License: https://creativecommons.org/licenses/by/4.0/

ClinicalTrials.gov record

Registration

Registration: NCT07573163
Study type: INTERVENTIONAL
Allocation: RANDOMIZED
Phase: PHASE2
Masking: NONE
Status: RECRUITING
Enrollment: 34
Start: 2026-07-27
Primary completion: 2028-07-31
Lead sponsor: Alaa Sada
Conditions: Mild Autonomous Cortisol Secretion (MACS); Adrenalectomy; Status
Interventions: DRUG:Tirzepatide; OTHER:Standard medical treatment
Results posted: FALSE
Individual participant data sharing: NO

Registered primary outcomes

Change in systolic blood pressure [Baseline and 12 months]

Linked records (2)

Automatic links, confirmed or rejected during screening. A record citing this registration may be a secondary analysis, a commentary or a review that mentions the trial.

Record	Title	Year	Design	Identifiers	Link basis
R0018082	Tirzepatide and blood pressure reduction: stratified analyses of the SURMOUNT-1 randomised controlled trial. Krumholz HM, Heart (British Cardiac Society)	2024	Randomized trial	PMID 39084707 DOI	registry reference BACKGROUND:39084707
R0019593	Effect of tirzepatide on blood pressure and lipids: A meta-analysis of randomized controlled trials. Kanbay M, Diabetes, obesity & metabolism	2023	Systematic review	PMID 37700437 DOI	registry reference BACKGROUND:37700437