LivingGLP1
Study S000767

Chinese People's Liberation Army General Hospital

Registration

Registration
NCT02930265
Study type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
QUADRUPLE
Status
UNKNOWN
Enrollment
400
Start
2016-09
Primary completion
2018-02
Lead sponsor
Chinese PLA General Hospital
Conditions
Ischemic Cardiomyopathy
Interventions
DRUG:Liraglutide
Results posted
FALSE
Individual participant data sharing
NO

Registered primary outcomes

  • main adverse cardiovascular events [Followed up for 6 months after enrolled in the study]

Linked records (13)

Automatic links, confirmed or rejected during screening. A record citing this registration may be a secondary analysis, a commentary or a review that mentions the trial.
RecordTitleYearDesignIdentifiersLink basis
R0022060Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes.
Marso SP, The New England journal of medicine
2016Randomized trialPMID 27295427DOIregistry reference BACKGROUND:27295427
R0025982Effects of liraglutide on left ventricular function in patients with non-ST-segment elevation myocardial infarction.
Chen WR, Endocrine
2016Randomized trialPMID 26573925DOIregistry reference BACKGROUND:26573925
R0026048Effects of liraglutide on no-reflow in patients with acute ST-segment elevation myocardial infarction.
Chen WR, International journal of cardiology
2016Randomized trialPMID 26849684DOIregistry reference BACKGROUND:26849684
R0026061Liraglutide protects cardiac microvascular endothelial cells against hypoxia/reoxygenation injury through the suppression of the SR-Ca(2+)-XO-ROS axis via activation of the GLP-1R/PI3K/Akt/survivin pathways.
Zhang Y, Free radical biology & medicine
2016OtherPMID 27038735DOIregistry reference BACKGROUND:27038735
R0020721Effects of liraglutide on left ventricular function in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.
Chen WR, American heart journal
2015Randomized trialPMID 26542491DOIregistry reference BACKGROUND:26542491
R0026736Benefits of liraglutide treatment in overweight and obese older individuals with prediabetes.
Kim SH, Diabetes care
2013Randomized trialPMID 23835684DOIregistry reference BACKGROUND:23835684
R0021573Exenatide alters myocardial glucose transport and uptake depending on insulin resistance and increases myocardial blood flow in patients with type 2 diabetes.
Gejl M, The Journal of clinical endocrinology and metabolism
2012Randomized trialPMID 22544917DOIregistry reference BACKGROUND:22544917
R0023502Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction.
Lønborg J, European heart journal
2012Randomized trialPMID 21920963DOIregistry reference BACKGROUND:21920963
R0017606Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met+TZD).
Zinman B, Diabetes care
2009Randomized trialPMID 19289857DOIregistry reference BACKGROUND:19289857
R0019848Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)-2 study.
Nauck M, Diabetes care
2009Randomized trialPMID 18931095DOIregistry reference BACKGROUND:18931095
R0021038GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice.
Noyan-Ashraf MH, Diabetes
2009PreclinicalPMID 19151200DOIregistry reference BACKGROUND:19151200
R0025460Exenatide reduces infarct size and improves cardiac function in a porcine model of ischemia and reperfusion injury.
Timmers L, Journal of the American College of Cardiology
2009Randomized trialPMID 19195607DOIregistry reference BACKGROUND:19195607
R0027526Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial.
Garber A, Lancet (London, England)
2009Randomized trialPMID 18819705DOIregistry reference BACKGROUND:18819705