Study S000745

Clinical and Neurobehavioral Changes With GLP-1 (Glucagon-like Peptide-1) Discontinuation

Name: LivingGLP1 adjudicated trial data and network meta-analysis results
Creator: Ahmad Sofi-Mahmudi
License: https://creativecommons.org/licenses/by/4.0/

ClinicalTrials.gov record

Registration

Registration: NCT07387796
Acronym: CLIN-GLP1
Study type: INTERVENTIONAL
Masking: NONE
Status: RECRUITING
Enrollment: 40
Start: 2026-10
Primary completion: 2028-02
Lead sponsor: The University of Texas at Dallas
Conditions: Drug Discontinuation; Substance Use Disorders; Eating Behavior Changes; Tirzepatide
Interventions: OTHER:Discontinuation and Reinitiation of Tirzepatide
Results posted: FALSE
Individual participant data sharing: NO

Registered primary outcomes

Change From On-Treatment to Discontinuation and Re-Initiation in Food Cue-Evoked BOLD Response in Reward and Salience Brain Regions [Baseline (on tirzepatide), 3-4 weeks of discontinuation, and 6-8 weeks of re-initiation]

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