Study S000691

Effectiveness and Persistence of Therapy With GLP-1 Receptor Agonists in Clinical Practice. A Multicenter Retrospective Study

Name: LivingGLP1 adjudicated trial data and network meta-analysis results
Creator: Ahmad Sofi-Mahmudi
License: https://creativecommons.org/licenses/by/4.0/

ClinicalTrials.gov record

Registration

Registration: NCT03959865
Acronym: GLP-1REWIN
Study type: OBSERVATIONAL
Status: UNKNOWN
Enrollment: 6000
Start: 2018-12-19
Primary completion: 2019-02-11
Lead sponsor: University of Padova
Conditions: Type 2 Diabetes
Interventions: DRUG:Long-acting GLP-1RA; DRUG:Short-acting GLP-1RA; DRUG:Human-based GLP-1RA; DRUG:Exendin-based GLP-1RA; DRUG:Fixed ratio BI/GLP-1RA combination; DRUG:Flexible BI/GLP-1RA combination
Results posted: FALSE
Individual participant data sharing: NO

Registered primary outcomes

HbA1c [3-12 months]

Linked records (6)

Automatic links, confirmed or rejected during screening. A record citing this registration may be a secondary analysis, a commentary or a review that mentions the trial.

Record	Title	Year	Design	Identifiers	Link basis
R0013444	Fixed versus flexible combination of GLP-1 receptor agonists with basal insulin in type 2 diabetes: A retrospective multicentre comparative effectiveness study. Morieri ML, Diabetes, obesity & metabolism	2019	Nonrandomized study	PMID 31364233 DOI	cites ClinicalTrials.gov:NCT03959865; registry reference DERIVED:31364233
R0009725	Cardiovascular outcomes with glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes: a meta-analysis. Bethel MA, The lancet. Diabetes & endocrinology	2018	Systematic review	PMID 29221659 DOI	registry reference BACKGROUND:29221659
R0019278	Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Davies MJ, Diabetes care	2018	Narrative review	PMID 30291106 DOI	registry reference BACKGROUND:30291106
R0008853	Glucagon-like peptide-1 receptor agonists compared with basal insulins for the treatment of type 2 diabetes mellitus: a systematic review and meta-analysis. Singh S, Diabetes, obesity & metabolism	2017	Systematic review	PMID 27717130 DOI	registry reference BACKGROUND:27717130
R0011638	A meta-analysis comparing clinical effects of short- or long-acting GLP-1 receptor agonists versus insulin treatment from head-to-head studies in type 2 diabetic patients. Abd El Aziz MS, Diabetes, obesity & metabolism	2017	Systematic review	PMID 27717195 DOI	registry reference BACKGROUND:27717195
R0012518	Incretin-based therapies for type 2 diabetes mellitus. Lovshin JA, Nature reviews. Endocrinology	2009	Narrative review	PMID 19444259 DOI	registry reference BACKGROUND:19444259