Study S000617

Exenatide Once Weekly for Smoking Cessation: A Randomized Clinical Trial

Name: LivingGLP1 adjudicated trial data and network meta-analysis results
Creator: Ahmad Sofi-Mahmudi
License: https://creativecommons.org/licenses/by/4.0/

ClinicalTrials.gov record Study Protocol and Statistical Analysis Plan (PDF)

Registration

Registration: NCT02975297
Study type: INTERVENTIONAL
Allocation: RANDOMIZED
Phase: PHASE1; PHASE2
Masking: TRIPLE
Status: COMPLETED
Enrollment: 84
Start: 2016-07
Primary completion: 2020-01-03
Lead sponsor: The University of Texas Health Science Center, Houston
Conditions: Smoking Cessation
Interventions: DRUG:Exenatide; DRUG:NRT; BEHAVIORAL:Counseling; DRUG:Placebo
Results posted: TRUE
Individual participant data sharing: NO
Secondary identifiers: OTHER:CCTS Research Scholar Award

Registered primary outcomes

Number of Participants Who Self-Reported Abstinence and Who Were Biochemically Verified as Abstinent Via Expired CO Level of ≤ 5ppm [6 weeks]
Post-quit Craving as Assessed by the Questionnaire of Smoking Urges [6 weeks]
Withdrawal Symptoms as Assessed by the Wisconsin Smoking Withdrawal Scale [6 weeks]
Cue-induced Craving for Cigarettes Following Virtual Reality Exposure as Assessed by the Questionnaire of Smoking Urges [1 week]
Cue-induced Craving for Cigarettes Following Virtual Reality Exposure as Assessed by the Questionnaire of Smoking Urges [3 weeks]

Linked records (2)

Automatic links, confirmed or rejected during screening. A record citing this registration may be a secondary analysis, a commentary or a review that mentions the trial.

Record	Title	Year	Design	Identifiers	Link basis
R0008332	Exenatide Adjunct to Nicotine Patch Facilitates Smoking Cessation and May Reduce Post-Cessation Weight Gain: A Pilot Randomized Controlled Trial. Yammine L, Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco	2021	Randomized trial	PMID 33831213 DOI	cites ClinicalTrials.gov:NCT02975297; registry reference DERIVED:33831213
R0020868	Exenatide once weekly for smoking cessation: study protocol for a randomized clinical trial. Yammine L, Medicine	2018	Protocol	PMID 29480848 DOI	registry reference BACKGROUND:29480848