Study S000194

Effects of Glucagon-like Peptide-1 (GLP-1) Agonist in Neuro-reproductive Function in Obese Adolescent Females With Polycystic Ovary Syndrome (PCOS)

Name: LivingGLP1 adjudicated trial data and network meta-analysis results
Creator: Ahmad Sofi-Mahmudi
License: https://creativecommons.org/licenses/by/4.0/

ClinicalTrials.gov record

Registration

Registration: NCT07169136
Study type: OBSERVATIONAL
Status: RECRUITING
Enrollment: 20
Start: 2025-09-11
Primary completion: 2026-12
Lead sponsor: Nemours Children's Clinic
Conditions: Polycystic Ovarian Syndrome in Adolescent Females; Obesity (Disorder)
Interventions: DRUG:GLP-1 Receptor Agonists
Results posted: FALSE
Individual participant data sharing: YES

Registered primary outcomes

Change in LH pulse frequency after 4 months of GLP-1 agonist use. [Blood sampling will occur at study enrollment and then 4 months post intervention.]
Change in average levels of LH and FSH after 4 months of GLP-1 agonist use. [Blood sampling will occur at study enrollment and then 4 months post intervention.]
Change in average levels of Total testosterone and Estradiol after 4 months of GLP-1 agonist use. [Blood sampling will occur at study enrollment and then 4 months post intervention.]
Change in average levels of progesterone after 4 months of GLP-1 agonist use. [Blood sampling will occur at study enrollment and then 4 months post intervention.]
Change in LH amplitude. [Blood sampling will occur at study enrollment and then 4 months post intervention.]

Linked records (0)

Automatic links, confirmed or rejected during screening. A record citing this registration may be a secondary analysis, a commentary or a review that mentions the trial.

No records link to this registration yet.