Study S000132

The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity: A Pilot Study

Name: LivingGLP1 adjudicated trial data and network meta-analysis results
Creator: Ahmad Sofi-Mahmudi
License: https://creativecommons.org/licenses/by/4.0/

ClinicalTrials.gov record

Registration

Registration: NCT07218445
Study type: INTERVENTIONAL
Allocation: RANDOMIZED
Phase: PHASE4
Masking: QUADRUPLE
Status: RECRUITING
Enrollment: 40
Start: 2026-04-08
Primary completion: 2027-09-18
Lead sponsor: Mayo Clinic
Conditions: Obesity; Menopause Hot Flashes
Interventions: DRUG:Tirzepatide; DRUG:Placebo
Results posted: FALSE
Individual participant data sharing: NO

Registered primary outcomes

Change in Vasomotor Symptoms Frequency [Baseline, 24 weeks]
Change in Vasomotor Symptom Severity [Baseline, 24 weeks]
Aging Biomarkers: Cellular Senescence Markers in Plasma [24 weeks]
Difference between biological and chronological age [24 weeks]

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